The challenge of peptide nucleic acid synthesis

Authors: K. P. Nandhini, Danah Al Shaer, Fernando Albericio, Beatriz G. de la Torre

Published: 2023-04-03

DOI: 10.1039/d2cs00049k

Source: Full article

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Abstract

The main strategies for the synthesis of Peptide Nucleic Acids (PNAs): key molecules as DNA/RNA mimics that can hybridize complementary chains of nucleic acids with high affinity and specificity.