A closer look at amyloid ligands, and what they tell us about protein aggregates

Authors: Timothy S. Chisholm, Christopher A. Hunter

Published: 2023-12-20

DOI: 10.1039/d3cs00518f

Source: Full article

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Abstract

A database of over 2000 different ligands that bind amyloid fibrils (Aβ, tau, or αSyn) has been compiled and used to investigate the factors that influence binding affinity and selectivity.