Abstract 12881: Lnc(RNA)-ing COX-2 and Cardioprotection: A PACERR Story

Authors: Elizabeth J Hennessy, Garret A Fitzgerald

Published: 2023-12-19

DOI: 10.1161/circ.148.suppl_1.12881

Source: Full article


Abstract

NSAIDs are amongst the most commonly used drugs by adults, but their use is complicated by an increased risk of adverse cardiovascular events that are consequent to suppression of cyclooxygenase-2 (COX-2) dependent prostaglandin (PG) formation, particularly prostacyclin (PGI