Abstract 176: The Pathological Role of Aldose Reductase in Isolated Cardiomyocytes Undergoing Hypoxia / Reoxygenation After Prior Exposure to High Glucose Concentrations

Authors: Miriam J Walter, Masakazu Shiota, Zhu Li, Matthew B Barajas, Takuro Oyama, Matthias L Riess

Published: 2023-12-19

DOI: 10.1161/circ.148.suppl_1.176

Source: Full article

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Abstract

Hyperglycemia increases the vulnerability of the cardiovascular system to ischemia/reperfusion (IR) injury. There are currently no effective therapeutic strategies.