A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands

Authors: Kejia Li, Shijie Chen, Keyun Wang, Yan Wang, Lianji Xue, Yuying Ye, Zheng Fang, Jiawen Lyu, Haiyang Zhu, Yanan Li, Ting Yu, Feng Yang, Xiaolei Zhang, Siqi Guo, Chengfei Ruan, Jiahua Zhou, Qi Wang, Mingming Dong, Cheng Luo, Mingliang Ye

Published: 2024-12-10

DOI: 10.1038/s41592-024-02553-7

Source: Full article

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Abstract

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