Cell-free synthetic biology for natural product biosynthesis and discovery

Authors: Andrew J. Rice, Tien T. Sword, Kameshwari Chengan, Douglas A. Mitchell, Nigel J. Mouncey, Simon J. Moore, Constance B. Bailey

Published: 2025-03-19

DOI: 10.1039/d4cs01198h

Source: Full article

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Abstract

Cell free synthetic biology enables a broad range of approaches relevant to the generation, biosynthetic characterisation, bioengineering, activity profiling, and production of complex natural products.