Direct photoreception by pituitary endocrine cells regulates hormone release and pigmentation

Authors: Ayaka Fukuda, Keita Sato, Chika Fujimori, Takahiro Yamashita, Atsuko Takeuchi, Hideyo Ohuchi, Chie Umatani, Shinji Kanda

Published: 2025-01-02

DOI: 10.1126/science.adj9687

Source: Full article


Abstract

The recent discovery of nonvisual photoreceptors in various organs has raised expectations for uncovering their roles and underlying mechanisms. In this work, we identified a previously unrecognized hormone-releasing mechanism in the pituitary of the Japanese rice fish (medaka) induced by light. Ca