Authors: Matthew J. Hangauer, Jorge Silvio Gutkind, Fleur M. Ferguson
Published: 2024-07-01
DOI: 10.1158/2159-8290.cd-24-0539
Source: Full article
Summary:In this issue, Ryan and colleagues describe the preclinical development of a pan-RAF:MEK molecular glue with superior efficacy, brain penetrance, and tolerability in xenograft models of Ras/Raf/MAPK pathway–driven tumors.See related article by Ryan et al., p. 1190 (1).