Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins

Authors: Malwina Hyjek-Składanowska, Timothy A. Vickers, Agnieszka Napiórkowska, Brooke A. Anderson, Michael Tanowitz, Stanley T. Crooke, Xue-hai Liang, Punit P. Seth, Marcin Nowotny

Published: 2020-03-23

DOI: 10.1021/jacs.9b13524

Source: Full article


Abstract

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