Engineering nanoparticles to locally activate T cells in the tumor microenvironment

Authors: Dangge Wang, Tingting Wang, Haijun Yu, Bing Feng, Lei Zhou, Fangyuan Zhou, Bo Hou, Hanwu Zhang, Min Luo, Yaping Li

Published: 2019-07-12

DOI: 10.1126/sciimmunol.aau6584

Source: Full article

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Abstract

Engineered antibody nanoparticles overcome immunological tolerance to PDL1 blockade therapy.