Abstract 246: Applying a Quantitative, Cell Surface Glycoproteomic Approach to Understanding the Role of Human Cardiac Fibroblasts in Advanced Heart Failure

Authors: Linda Berg Luecke, Amanda R Buchberger, Matthew Waas, Claudius Mahr, Rebekah L Gundry

Published: 2019-10-16

DOI: 10.1161/res.125.suppl_1.246

Source: Full article

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Abstract

Heart Failure (HF) is a complex clinical syndrome defined by the heart’s inability to adequately perfuse the human body. The clinical progression of HF has been linked to the pathological activation of CF, which contributes to adverse remodeling and cardiac fibrosis. Previous studies have shown that unloading the failing heart