Abstract 372: CRISPR-based Gene Activation for Transcriptional Reprograming of Mammalian Cardiomyocytes

Authors: Eric Schoger, Kelli J Carroll, John McAnally, Wei Tan, Norman Liaw, Lavanya M Iyer, Claudia Noack, Wolfram H Zimmermann, Rhonda Bassel-Duby, Laura C Zelarayan

Published: 2019-10-16

DOI: 10.1161/res.125.suppl_1.372

Source: Full article

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Abstract

Cardiac remodelling is accompanied by silencing of genes necessary for cardiac homeostasis including Krüppel-like factor 15 (