Benzylic Dehydroxylation of Echinocandin Antifungal Drugs Restores Efficacy against Resistance Conferred by Mutated Glucan Synthase

Authors: Dana Logviniuk, Qais Z. Jaber, Roman Dobrovetsky, Noga Kozer, Ewa Ksiezopolska, Toni Gabaldón, Shmuel Carmeli, Micha Fridman

Published: 2022-03-29

DOI: 10.1021/jacs.2c00269

Source: Full article

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Abstract

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