Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage

Authors: Huanyi Fu, Rongdiao Liu, Zixuan Jia, Ran Li, Feifeng Zhu, Wenxuan Zhu, Yangqing Shao, Yiyang Jin, Yuhua Xue, Jun Huang, Kunxin Luo, Xiang Gao, Huasong Lu, Qiang Zhou

Published: 2022-04-07

DOI: 10.1038/s41556-022-00872-5

Source: Full article

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Abstract

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