All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages

Authors: Enyu Rao, Yuzhu Hou, Xiaona Huang, Liangliang Wang, Jiaai Wang, Wenxin Zheng, Hengjin Yang, Xinshuang Yu, Kaiting Yang, Jason Bugno, Xingchen Ding, Everett E. Vokes, Yang-Xin Fu, Ralph R. Weichselbaum, Hua Laura Liang

Published: 2021-10-14

DOI: 10.1126/sciimmunol.aba8426

Source: Full article

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Abstract

All-trans retinoic acid induces inflammatory myeloid cells to enhance antitumor adaptive immunity after radiation therapy.