Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation

Authors: Lesly Calderón, Karina Schindler, Stephen G. Malin, Alexandra Schebesta, Qiong Sun, Tanja Schwickert, Chiara Alberti, Maria Fischer, Markus Jaritz, Hiromi Tagoh, Anja Ebert, Martina Minnich, Adrian Liston, Luisa Cochella, Meinrad Busslinger

Published: 2021-07-23

DOI: 10.1126/sciimmunol.abg5003

Source: Full article

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Abstract

Pax5 controls the generation, proliferation, and survival of all mature B cells by promoting PI3K signaling via PTEN down-regulation.