TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy

Authors: Rinkesh K. Gupta, Donald T. Gracias, Daniela Salgado Figueroa, Haruka Miki, Jacqueline Miller, Kai Fung, Ferhat Ay, Linda Burkly, Michael Croft

Published: 2021-11-19

DOI: 10.1126/sciimmunol.abi8823

Source: Full article

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Abstract

TWEAK synergizes with TNF and IL-17 in keratinocytes to drive psoriasis-like skin inflammation.