Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors

Authors: Katrina M. Lappin, Eliana M. Barros, Satpal S. Jhujh, Gareth W. Irwin, Hayley McMillan, Fabio G. Liberante, Cheryl Latimer, Melissa J. La Bonte, Ken I. Mills, D. Paul Harkin, Grant S. Stewart, Kienan I. Savage

Published: 2022-01-13

DOI: 10.1158/0008-5472.can-21-1843

Source: Full article

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors

Abstract