Deciphering the Multi-state Conformational Equilibrium of HDM2 in the Regulation of p53 Binding: Perspectives from Molecular Dynamics Simulation and NMR Analysis

Authors: Kazuki Watanabe, Qingci Zhao, Ryosuke Iwatsuki, Ryota Fukui, Weitong Ren, Yuji Sugita, Noritaka Nishida

Published: 2024-03-29

DOI: 10.1021/jacs.3c14383

Source: Full article

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Abstract

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