Authors: Yuanchi Zhang, Cairong Li, Along Guo, Yipei Yang, Yangyi Nie, Jiaxin Liao, Ben Liu, Yanmei Zhou, Long Li, Zhitong Chen, Wei Zhang, Ling Qin, Yuxiao Lai
Published: 2024-02-22
DOI: 10.1038/s41467-024-46003-6
Source: Full article
AbstractWet-tissue adhesives have long been attractive materials for realizing complicated biomedical functions. However, the hydration film on wet tissues can generate a boundary, forming hydrogen bonds with the adhesives that weaken adhesive strength. Introducing black phosphorus (BP) is believed to enhance the water absorption capacity of tape-type adhesives and effectively eliminate hydration layers between the tissue and adhesive. This study reports a composite patch integrated with BP nanosheets (CPB) for wet-tissue adhesion. The patch’s improved water absorption and mechanical properties ensure its immediate and robust adhesion to wet tissues. Various bioapplications of CPB are demonstrated, such as rapid hemostasis (within ~1-2 seconds), monitoring of physical-activity and prevention of tumour-recurrence, all validated via in vivo studies. Given the good practicability, histocompatibility and biodegradability of CPB, the proposed patches hold significant promise for a wide range of biomedical applications.