Listen to your gut: Antibodies against gut commensals predict type 1 diabetes onset and therapeutic responses to T cell modulation

Authors: Rachael A. Clark

Published: 2023-12-01

DOI: 10.1126/sciimmunol.adn0649

Source: Full article

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Abstract

Immune responses to gut bacteria are associated with development of type 1 diabetes and predict the effectiveness of teplizumab, an anti-CD3 antibody, in delaying diabetes onset.