Efficacy, safety, pharmacokinetics, and associated microbiome changes of ibezapolstat compared with vancomycin in adults with Clostridioides difficile infection: a phase 2b, randomised, double-blind, active-controlled, multicentre study

Authors: Taryn A Eubank, Jinhee Jo, M Jahangir Alam, Khurshida Begum, Jacob K McPherson, ThanhPhuong M Le, Thomas D Horvath, Sigmund J Haidacher, Eugene C Poggio, Rong Lin, Corinne Seng Yue, Murray P Ducharme, Georges Koudssi, Julie Mercier, Jeffrey D Alder, Michael H Silverman, Kevin W Garey, Richard Nathan, John Pullman, Belkis Delgado, Idania Garcia Del Sol, Robert Brennan, Erick Juarez, Florin Gaidici, Harry Schrager, Yunior Silva-Barrero, Christopher Connolley, Michael DiGiovanna

Published: 2025-06-11

DOI: 10.1016/j.lanmic.2025.101126

Source: Full article

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Abstract

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