Characterization and Engineering of a Bisabolene Synthase Reveal an Unusual Hydride Shift and Key Residues Critical for Mono-, Bi-, and Tricyclic Sesquiterpenes Formation

Authors: Mengyue Wu, Ian Torrence, Yuanning Liu, Jingshuai Wu, Rui Ge, Ke Ma, Dong Liu, Jinwei Ren, Shilong Fan, Ming Ma, Justin B. Siegel, Dean J. Tantillo, Wenhan Lin, Aili Fan

Published: 2025-03-12

DOI: 10.1021/jacs.4c17818

Source: Full article

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Abstract

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