Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation

Authors: Sujin Park, Kwiyeom Yoon, Eunji Hong, Min Woo Kim, Min Gi Kang, Seiya Mizuno, Hye Jin Kim, Min-Jung Lee, Hee Jae Choi, Jin Sun Heo, Jin Beom Bae, Haein An, Naim Park, Hyeyeon Park, Pyunggang Kim, Minjung Son, Kyoungwha Pang, Je Yeun Park, Satoru Takahashi, Yong Jung Kwon, Dong-Woo Kang, Seong-Jin Kim

Published: 2025-03-24

DOI: 10.1038/s41413-025-00419-y

Source: Full article

Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation

Abstract