DNA damage response defects induced by the formation of TDP-43 and mutant FUS cytoplasmic inclusions and their pharmacological rescue

Authors: Stefania Modafferi, Stefania Farina, Francesca Esposito, Ornella Brandi, Michela Di Salvio, Ilaria Della Valle, Sara D’Uva, Eveljn Scarian, Giada Cicio, Adelaide Riccardi, Federica Pisati, Anna Garbelli, Tiziana Santini, Orietta Pansarasa, Mariangela Morlando, Nadia D’Ambrosi, Mauro Cozzolino, Gianluca Cestra, Fabrizio d’Adda di Fagagna, Ubaldo Gioia, Sofia Francia

Published: 2025-05-29

DOI: 10.1038/s41418-025-01530-7

Source: Full article

DNA damage response defects induced by the formation of TDP-43 and mutant FUS cytoplasmic inclusions and their pharmacological rescue

Abstract