Recapitulating hypoxic metabolism in cartilaginous organoids via adaptive cell-matrix interactions enhances histone lactylation and cartilage regeneration

Authors: Boguang Yang, Zhuo Li, Zhengmeng Yang, Pengchao Zhao, Sien Lin, Jiahao Wu, Wei Liu, Xuefeng Yang, Xian Xie, Zhixian Zong, Yuanning Lyu, Zhinan Yang, Gang Li, To Ngai, Kunyu Zhang, Liming Bian

Published: 2025-03-19

DOI: 10.1038/s41467-025-57779-6

Source: Full article

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Abstract

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