Inhibitor-based modulation of huntingtin aggregation mechanisms mitigates fibril-induced cellular stress

Authors: Greeshma Jain, Marina Trombetta-Lima, Irina Matlahov, Hennrique Taborda Ribas, Tingting Chen, Raffaella Parlato, Giuseppe Portale, Amalia M. Dolga, Patrick C. A. van der Wel

Published: 2025-04-15

DOI: 10.1038/s41467-025-58691-9

Source: Full article

Inhibitor-based modulation of huntingtin aggregation mechanisms mitigates fibril-induced cellular stress

Abstract