Authors: Jie Xu, Lingzhi Zhang, Yanhui Duan, Fangyuan Sun, Nouha Odeh, Yuan He, Gabriel Núñez
Published: 2025-01-03
DOI: 10.1126/sciimmunol.adl2993
Source: Full article
The NLRP3 inflammasome plays a critical role in innate immunity and inflammatory diseases. NIMA-related kinase 7 (NEK7) is essential for inflammasome activation, and its interaction with NLRP3 is enhanced by K