Molecular scalpels dissect new GluN1 hot spots in anti–NMDA receptor encephalitis

Authors: Marianna Spatola, Josep Dalmau

Published: 2025-01-03

DOI: 10.1126/sciimmunol.adv4913

Source: Full article

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Abstract

Patient-derived NMDAR mAbs combined with single-particle cryo-electron microscopy reveal multiple GluN1 epitopes and distinct functional effects.