¹H and ³¹P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID

Authors: Lucy E. M. Finnigan, Mark Philip Cassar, Mehrsa Jafarpour, Antonella Sultana, Zakariye Ashkir, Karim Azer, Stefan Neubauer, Damian J. Tyler, Betty Raman, Ladislav Valkovič

Published: 2024-12-24

DOI: 10.1148/radiol.233173

Source: Full article

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Abstract

MR spectroscopy showed altered phosphocreatine recovery and mitochondrial capacity in participants with post–COVID-19 condition, also called long COVID, compared with controls, suggesting mitochondrial dysfunction; however, these changes did not correlate with fatigue severity.