A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair

Authors: Jennifer Castro, Matthew H. Daniels, David Brennan, Brian Johnston, Deepali Gotur, Young-Tae Lee, Kevin E. Knockenhauer, Chuang Lu, Jie Wu, Sunaina Nayak, Cindy Collins, Rishabh Bansal, Shane M. Buker, April Case, Julie Liu, Shihua Yao, Brian A. Sparling, E. Allen Sickmier, Serena J. Silver, Stephen J. Blakemore, P. Ann Boriack-Sjodin, Kenneth W. Duncan, Scott Ribich, Robert A. Copeland

Published: 2024-11-26

DOI: 10.1158/0008-5472.can-24-0397

Source: Full article


Abstract

Abstract