Abstract 1165: The landscape of molecular targets across 665 next-generation cancer models in the human cancer models initiative identifies opportunities for improved therapy and overcoming resistance

Authors: Dina ElHarouni, Mushriq Al-Jazrawe, Seongmin Choi, Merve Dede, Toshinori Hinoue, Sean A. Misek, Heeju Noh, Luca Zanella, Moony Tseng, Hayley E. Francies, Priya Sridevi, Rachana Agarwal, Cindy W. Kyi, Julyann Perez-Mayoral, Megan J. Stine, Eva Tonsing-Carter, James M. Clinton, William F. Hooper, Jennifer M. Shelton, Timothy R. Chu, The HCMI Network, Peter W. Laird, Calvin J. Kuo, Olivier Elemento, David L. Spector, Andrew D. Cherniack, Kyle Ellrott, Martin L. Ferguson, Rameen Beroukhim, Katherine A. Hoadley, Nicolas Robine, Andrew McPherson, Mathew J. Garnett, David A. Tuveson, Andrea Califano, Paul T. Spellman, Keith L. Ligon, Daniela S. Gerhard, Louis M. Staudt, Jesse S. Boehm

Published: 2025-04-22

DOI: 10.1158/1538-7445.am2025-1165

Source: Full article


Abstract

Abstract