Abstract 2363: PRMT5 as a target in CRC interception: Synthetic lethal dependency identified in APC-LOF preclinical models of FAP disease

Authors: Dana S. Gaffney, Jan Willem Thuring, Fabian Hulpia, Eileen Vesely, Edward Retzbach, Zienab Etwebi, Zhengyu Jiang, Albi Francis, Bethany Mattson, Victoria Wong, Mariana Silva, Gerben ten Hag, Rene Overmeer, Carla Verissimo, Sylvia F. Boj, Johan Nicolai, Mark Hixon, Gerry Chu, Andrea DiSandro, Kathleen Clancy, Alexandra Liddane, Kurtis Bachman, David Pocalyko

Published: 2025-04-21

DOI: 10.1158/1538-7445.am2025-2363

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