Abstract 6296: Unlocking scalable and efficient multiomic analysis of 5- and 6-base genomes

Authors: Sabri Jamal, Michael J. Wilson, Jean Teyssandier, Gary Frewin, Mark S. Hill, William Stark, Nicola Wong, Robert Blanshard, Andrada Tomoni, Tom Charlesworth, Nicholas J. Harding, Páidí Creed

Published: 2025-04-21

DOI: 10.1158/1538-7445.am2025-6296

Source: Full article


Abstract

We present a computational toolkit to analyze 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) Cytosine modifications at scale and describe its performance on a liquid biopsy dataset.