Abstract LB374: Chronic emotional distress in lung cancer is associated with attenuated IFN-gamma-signaling and dysfunctional T cells, diminished response to immune checkpoint blockade and adverse outcome

Authors: Barbara Katharina Geist, Chrysoula Vraka, Thomas Selim Nakuz, Karolina Trachtova, Song Xue, Chengcheng Shi, Kilian Kluge, Oana Kulterer, Josef Yu, Laurin Herbsthofer, Alessandro Liebich, Martina Tomberger, Thomas Schweiger, Helmut Prosch, Felicitas Oberndorfer, Constantin Lapa, Xinli Xie, Hong Zong, Lukas Kenner, Stefan Gruenert, Marcus Hacker

Published: 2025-04-25

DOI: 10.1158/1538-7445.am2025-lb374

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