Abstract Tu001: MiR-21 mitigated pulmonary hypertension induced right ventricular dysfunction through pulmonary circulating exosomes

Authors: Wei-Ting Chang, Sudeshna Fisch, Chih-Hsin Hsu

Published: 2024-10-09

DOI: 10.1161/res.135.suppl_1.tu001

Source: Full article

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Abstract

Background: Patients with pulmonary arterial hypertension (PAH) often experience adverse outcomes primarily due to right ventricular (RV) dysfunction. However, the intricate relationship between pulmonary circulation and RV remodeling remains largely unexplored. Exosomal microRNAs (miRNAs) function as paracrine signaling mediators in diverse diseases.