Abstract Tu138: Tandem Mass Tagging (TMT)-based Identification of Proteome Signatures for Ischemia-Reperfusion Injury in Swine

Authors: Sini Sunny, Jiacheng Sun, Sayed Aniqa, Gregory Walcott, Jianyi Zhang, Rajasekaran Namakkal-Soorappan

Published: 2024-10-09

DOI: 10.1161/res.135.suppl_1.tu138

Source: Full article


Abstract

Background: The composition of proteins in blood plasma mirrors the physical changes occurring in the course of disease pathogenesis. Currently available clinical markers are insufficient to predict the actual damage and the redox changes in response to ischemia. Hence, we identified novel redox markers for ischemia/reperfusion (I/R) in swine using TMT-proteomics.