Authors: Jamie Francisco, Satvik Mareedu, Jin Guan, Eun-Ah Sung, Peiyong Zhai, Che-Ming Hu, Dominic Del Re
Published: 2024-10-09
DOI: 10.1161/res.135.suppl_1.we070
Source: Full article
Background: There is a growing appreciation that neutrophils demonstrate plasticity, not unlike the macrophage, and can modulate both inflammation and repair following organ injury. Neutrophils are rapidly recruited to the heart after acute myocardial infarction (MI) and participate in cardiac inflammation and remodeling. Nevertheless, mechanisms regulating neutrophil function during heart injury remain largely unknown.