Authors: Stephen J. Walsh, Jonathan D. Bargh, Friederike M. Dannheim, Abigail R. Hanby, Hikaru Seki, Andrew J. Counsell, Xiaoxu Ou, Elaine Fowler, Nicola Ashman, Yuri Takada, Albert Isidro-Llobet, Jeremy S. Parker, Jason S. Carroll, David R. Spring
Published: 2020-12-10
DOI: 10.1039/d0cs00310g
Source: Full article
Antibody–drug conjugates (ADCs) harness the highly specific targeting capabilities of an antibody to deliver a cytotoxic payload to specific cell types. This review summarises the advances made in the construction of homogenous ADCs.