Recent progress in non-native nucleic acid modifications

Authors: Luke K. McKenzie, Roberto El-Khoury, James D. Thorpe, Masad J. Damha, Marcel Hollenstein

Published: 2021-03-01

DOI: 10.1039/d0cs01430c

Source: Full article


Abstract

While Nature harnesses RNA and DNA to store, read and write genetic information, the inherent programmability, synthetic accessibility and wide functionality of these nucleic acids make them attractive tools for use in a vast array of applications.