Extracellular vesicles from myelodysplastic mesenchymal stromal cells induce DNA damage and mutagenesis of hematopoietic stem cells through miRNA transfer

Authors: Mathieu Meunier, Audrey Guttin, Sarah Ancelet, David Laurin, Johanna Zannoni, Christine Lefebvre, Sylvie Tondeur, Virginie Persoons, Mylène Pezet, Karin Pernet-Gallay, Florent Chuffart, Sophie Rousseaux, Quentin Testard, Julien Thevenon, Claire Jouzier, Jean-François Deleuze, Karine Laulagnier, Rémy Sadoul, Christine Chatellard, Pierre Hainaut, Benoît Polack, Jean-Yves Cahn, Jean-Paul Issartel, Sophie Park

Published: 2020-02-12

DOI: 10.1038/s41375-020-0738-8

Source: Full article

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Abstract

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