PB1845 THE EFFICACY OF TRANEXAMIC ACID IN MINOR SURGERY WITH BLEEDING DISORDERS PATIENTS: 17 YEARS EXPERIENCE AT UNIVERSITY HOSPITAL

Authors: S. Al Jaouni, D. Farsi, S. Al Muhayawi

Published: 2019-06-17

DOI: 10.1097/01.hs9.0000565884.42722.ed

Source: Full article


Abstract

Background:Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to reduce blood loss in different medical disorders.Aims:To assess the efficacy and outcome to use TXA in dental work with patient with bleeding disorders at our institute over 17 years period.Methods:This is a retrospective study to assess the efficacy of the TXA in all dental works for patients with bleeding disorders treated at King Abdulaziz University Hospital (KAUH) at King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia, between 2000‐2017, also to assess the requirements of transfusion after the procedures.Results:One hundred twenty one patients with bleeding disorders underwent dental and minor surgery over 17 years with patient age range 3‐46 years. Tropical oral TXA in majority of the cases only 5% used intravenous TXA in hospitalized patients. Less than 5% required transfusion after the procedures.Summary/Conclusion:Strong evidence supports the use of TXA in minor surgery with bleeding disorders in our institute over 17 years. Markedly decrease and minimize the need of transfusion after use TXA in dental works.