YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

Authors: Hirofumi Omori, Miki Nishio, Muneyuki Masuda, Yosuke Miyachi, Fumihito Ueda, Takafumi Nakano, Kuniaki Sato, Koshi Mimori, Kenichi Taguchi, Hiroki Hikasa, Hiroshi Nishina, Hironori Tashiro, Tohru Kiyono, Tak Wah Mak, Kazuwa Nakao, Takashi Nakagawa, Tomohiko Maehama, Akira Suzuki

Published: 2020-03-18

DOI: 10.1126/sciadv.aay3324

Source: Full article

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Abstract

MOB1 deficiency promotes rapid onset and progression of oral SCC (OSCC) via YAP1 activation.