Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy

Authors: Jin-Mi Heo, Nathan J. Harper, Joao A. Paulo, Mamie Li, Qikai Xu, Margaret Coughlin, Stephen J. Elledge, J. Wade Harper

Published: 2019-11-07

DOI: 10.1126/sciadv.aay4624

Source: Full article

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Abstract

We explore the landscape of a mitochondrial-autophagosome synapse during mitophagy using proteomics and genetic screens.