Isothermal digital detection of microRNAs using background-free molecular circuit

Authors: Guillaume Gines, Roberta Menezes, Kaori Nara, Anne-Sophie Kirstetter, Valerie Taly, Yannick Rondelez

Published: 2020-01-23

DOI: 10.1126/sciadv.aay5952

Source: Full article

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Abstract

We report the isothermal digital detection of microRNAs using DNA circuits encoding a background-free amplification mechanism.