Targeted pathological collagen delivery of sustained-release rapamycin to prevent heterotopic ossification

Authors: Yangwu Chen, Weiliang Shen, Chenqi Tang, Jiayun Huang, Chunmei Fan, Zi Yin, Yejun Hu, Weishan Chen, Hongwei Ouyang, Yiting Zhou, Zhengwei Mao, Xiao Chen

Published: 2020-05-20

DOI: 10.1126/sciadv.aay9526

Source: Full article

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Abstract

We revealed the importance of mTOR in tendon HO and established a drug delivery system that targets pathological collagen.