MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy

Authors: Lingzhi Zhao, Junyao Li, Yaoquan Su, Liqiang Yang, Liu Chen, Lei Qiang, Yajing Wang, Huijing Xiang, Huijun Phoebe Tham, Juanjuan Peng, Yanli Zhao

Published: 2020-03-05

DOI: 10.1126/sciadv.aaz0575

Source: Full article

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Abstract

An MTH1 inhibitor is integrated with nanoparticles to enhance therapy effect of reactive oxygen species in cancer treatment.