The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks

Authors: Alberto Jiménez-Martín, Irene Saugar, Chinnu Rose Joseph, Alexandra Mayer, Carl P. Lehmann, Barnabas Szakal, Dana Branzei, José Antonio Tercero

Published: 2020-04-08

DOI: 10.1126/sciadv.aaz3327

Source: Full article


Abstract

Mgs1 contributes to genome stability by helping to avoid unwanted recombination at sites of perturbed DNA replication.