Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation

Authors: Chunmei Ma, Dongxue Yang, Bingwei Wang, Chunyan Wu, Yuqing Wu, Sheng Li, Xue Liu, Kara Lassen, Lue Dai, Shuo Yang

Published: 2020-05-20

DOI: 10.1126/sciadv.aaz6717

Source: Full article

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Abstract

Gasdermin D in colonic macrophages controls cGAS-mediated inflammation, thereby protecting against the development of colitis.