Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment

Authors: Leiming Wang, Chiang-Min Cheng, Jun Qin, Mafei Xu, Chung-Yang Kao, Jingjing Shi, Erli You, Wanchun Gong, Laura Pedro Rosa, Peter Chase, Louis Scampavia, Franck Madoux, Timothy Spicer, Peter Hodder, H. Eric Xu, Sophia Y. Tsai, Ming-Jer Tsai

Published: 2020-04-29

DOI: 10.1126/sciadv.aaz8031

Source: Full article

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Abstract

We identified inhibitors targeting COUP-TFII for the treatment of diseases including prostate cancer.